Fildena Chewable 100 mg contains sildenafil citrate as its active ingredient and is primarily used for the treatment of erectile dysfunction (ED) in adult men. It's important to be aware of potential interactions between Fildena Chewable 100 mg and other medications, as these interactions can affect the safety, effectiveness, and side effects of both medications. Here are some important points to consider:
Nitrates: The combination of Fildena Chewable 100 mgwith nitrates, such as nitroglycerin or isosorbide mononitrate/dinitrate, used to treat chest pain (angina), can cause a significant drop in blood pressure. Concurrent use of sildenafil citrate with nitrates is contraindicated and can lead to a life-threatening hypotensive crisis.
Alpha-Blockers: Alpha-blockers, such as doxazosin, terazosin, or tamsulosin, used to treat high blood pressure or prostate enlargement, can also cause a drop in blood pressure when combined with sildenafil citrate. Caution is advised when using these medications together, and dosage adjustments may be necessary.
Antihypertensive Agents: Other antihypertensive medications, such as beta-blockers, calcium channel blockers, or ACE inhibitors, may potentiate the hypotensive effects of sildenafil citrate. Close monitoring of blood pressure is recommended when using these medications concurrently.
Antifungal Agents: Certain antifungal medications, such as ketoconazole or itraconazole, can inhibit the metabolism of sildenafil citrate, leading to increased sildenafil levels in the blood. This can increase the risk of side effects and adverse reactions. Dosage adjustments may be necessary when using these medications together.
HIV Protease Inhibitors: HIV protease inhibitors, such as ritonavir or saquinavir, can also inhibit the metabolism of sildenafil citrate, leading to increased sildenafil levels in the blood. This can increase the risk of side effects and adverse reactions. Dosage adjustments may be necessary when using these medications together.
Other Medications: Other medications that affect the liver enzyme cytochrome P450 3A4 (CYP3A4), such as certain antibiotics, anticonvulsants, and herbal supplements, may also affect the metabolism of sildenafil citrate and should be used with caution.
It's important to inform your healthcare provider about all medications you are taking, including prescription, over-the-counter, and herbal supplements, before starting Fildena Chewable 100 mg or any other medication containing sildenafil citrate. Your healthcare provider can help determine the safety and appropriateness of using these medications together and make any necessary adjustments to your treatment regimen.